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Efficacy of acupuncture in prevention of postoperative anaesthesia-related shivering
  1. Saeed Shoar1,2,3,
  2. Sara Esmaeili2,3,
  3. Zhamak Khorgami1,
  4. Mohammad Naderan1,2,
  5. Nasrin Shoar2,4
  1. 1Department of Surgery, Shariati Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2Development Association of Clinical Studies (DACS), Student Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran
  3. 3Department of Acupuncture Medicine, Tehran University of Medical Sciences, Tehran, Iran
  4. 4Department of Medicine, Shahid Beheshti Hospital, Kashan University of Medical Sciences (KUMS), Kashan, Iran
  1. Correspondence to Dr Nasrin Shaor, Development Association of Clinical Studies (DACS), Student Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran, No 12345, School of Medicine, Poorsina Street, Qods Street, Keshavarz Boulevard, Tehran, Iran; nasrinshoar{at}

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Postoperative shivering still occurs as a complication of general anaesthesia.1 ,2 Shivering depends on age, sex, duration of anaesthesia and type of anaesthetic agent(s).1–3 Primarily due to anaesthetic agents such as isoflurane, this type of shivering presents as spontaneous muscular activity in patients with normal body temperature after general anaesthesia for specific operations.4 ,5 With advances in alternative medicine in recent decades, acupuncture is increasingly known as an effective method in managing complications of surgery and anaesthesia. However, the most efficacious point of stimulation still needs investigation.

A prospective non-randomised clinical study was performed on 228 patients admitted to the department of surgery at Shariati Hospital between March 2011 and June 2011. The Research Ethics committee of Tehran University of Medical Sciences in Tehran, Iran approved the study protocol on human subjects and patients completed an informed consent before entering the study. Patients received general anaesthesia for elective surgery with standardised surgical techniques performed by one of the authors (ZK). Anaesthesia was induced with sodium thiopental (5 mg/kg) and atracurium besylate (0.5 mg/kg) followed by midazolam (0.03 mg/kg) and fentanyl (2.5 µg/kg). After tracheal intubation, subjects were mechanically ventilated with a mixture of 50% O2 and 50% N2O. Standard monitoring was performed during the surgery. Anaesthesia was maintained with 1 minimum alveolar concentration isoflurane, inspired at a fresh gas flow rate of 4 litres/min. Further, boluses of fentanyl (1 µg/kg) and atracurium besylate (0.2 mg/kg) were given every 30 min.

A total of 115 subjects were assigned into the case group with concomitant stimulation of PC6 and LI4 points while 113 patients in the control group was treated by acupuncture only at the PC6 point. Sterile needles (Energy, China) with a diameter of 0.2 mm were inserted to 5 mm depth of acupuncture points following induction of anaesthesia, rotated for 5–10 s and kept in situ until the end of the operation.

The mean±SD age of patients and male/female ratio did not differ significantly between the single group and the combined group (p>0.05) (table 1). There was also no significant difference between the two groups in terms of surgical procedures and protocol of anaesthesia. Shivering occurred in 11 patients (9.6%) in the combined group compared to 29 patients (25.7%) in the single group, which revealed a statistically significant difference (p=0.001). However, the incidence of postoperative shivering in our study was low (overall 17.5%). A lower incidence of postoperative shivering occurs as a result of improved anaesthetic protocol over time and administration of prophylactic anaesthetic regimens,6 which were not different between our groups. Although acupuncture has shown benefits for management of postoperative complications,7 ,8 no study has compared the effectiveness of stimulation of different acupuncture points on postoperative anaesthesia-related shivering. Our experience with this group of patients showed that combined stimulation of PC6 and LI4 points is associated with lower incidence of postoperative shivering. We could find no published study on this topic with which to compare our findings. Hence, further investigations are needed before any recommendation on the use of acupuncture can be made.

Table 1

Demographics and primary characteristics of patients


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  • Contributors SS analysed the data, drafted the manuscript and critically reviewed and revised it. SE had the original idea for the work, interpreted the study findings and drafted the manuscript. ZK supervised the work, interpreted the results and critically reviewed the work. MN participated in data collection, interpreting the results and drafting of the manuscript. NS had the original idea for the work, analysed the data and critically reviewed the whole work.

  • Competing interests None.

  • Ethics approval Research and Ethic Committee of Tehran University of Medical Sciences.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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