Table 2

Summary of findings

Acupuncture vs no treatment during IVF or ICSI in women with PCOS
Patient or population: patients with PCOS undergoing IVF
Setting: RCT
Intervention: acupuncture
Comparison: control (no acupuncture)
Illustrative comparative risks* (95% CI)Relative effect
(95% CI)
No. of participants
(studies)
Level of evidence
(GRADE)
Comments
OutcomesAssumed riskCorresponding risk
ComparisonAcupuncture
Live birth rate219 per 1000352 per 1000
(153 to 619)
RR 1.61
(0.73 to 3.58)
66 (1 study)⊕⊕⊝⊝
low†‡
Clinical pregnancy rate287 per 1000387 per 1000
(301 to 499)
RR 1.35
(1.05 to 1.74)
430 (4 studies)⊕⊕⊝⊝
low†‡
Ongoing pregnancy rate140 per 1000279 per 1000
(148 to 524)
RR 1.99
(1.06 to 3.74)
164 (2 studies)⊕⊕⊝⊝
low†‡
OHSS296 per 1000190 per 1000
(127 to 288)
RR 0.64
(0.43 to 0.97)
368 (3 studies)⊕⊕⊝⊝
low†‡
  • *The basis for the assumed risk (eg, the median control group risk across studies) is provided in the footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

  • †Serious risk of bias as a result of randomisation and allocation concealment.

  • ‡Low number of participants.

  • GRADE, Grades of Recommendations, Assessment, Development and Evaluation; ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization; OHSS, ovarian hyperstimulation syndrome; PCOS, polycystic ovarian syndrome; RCT, randomized controlled trial; RR, risk ratio.