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Could acupuncture at the so-called forbidden points be harmful to the health of pregnant Wistar rats?
  1. André Vilella Guerreiro da Silva1,2,
  2. Mary Uchiyama Nakamura1,
  3. João Bosco Guerreiro da Silva2,
  4. José Antonio Cordeiro3,
  5. Glória Elisa Mendes4,
  6. Luiz Lima5
  1. 1Department of Obstetrics, Federal University of São Paulo, São Paulo, Brazil
  2. 2Service of Acupuncture – Department of Medicine II – Rio Preto Medical School, São José do Rio Preto, Brazil
  3. 3Department of Statistics, Rio Preto Medical School, São José do Rio Preto, Brazil
  4. 4Department of Medicine I – Rio Preto Medical School, São José do Rio Preto, Brazil
  5. 5 Department of Pathology – Rio Preto Medical School, São José do Rio Preto, Brazil
  1. Correspondence to Professor João Bosco Guerreiro da Silva, Rio Preto Medical School, Rua Pernambuco, 3147 CEP, São José do Rio Preto, SP 15015-770, Brazil; jbgsilva{at}hotmail.com

Abstract

Aim This study is the second report from a single experiment planned to determine if acupuncture at LI4 and SP6, or at the sacral points, could produce any harm in the pregnancy outcome of Wistar rats, as has been hypothesised in traditional knowledge. Here, we observe if these points can be harmful to the health of pregnant Wistar rats.

Methods A total of 48 pregnant Wistar rats were randomly divided into 4 groups: total control, where rats were left in cages without manipulation; anesthetised control, where rats were manipulated and anesthetised but did not receive electroacupuncture; and peripheral point and sacral point groups, where rats were anesthetised and received 6 sessions of electroacupuncture at 4 acupuncture points: LI4 and SP6, and BL27 and BL28, respectively. In the 19th day of pregnancy the rats were killed and examined. The primary endpoints were levels of glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT) creatinine and histological changes of liver and kidney.

Results There were no differences between the levels of biochemical parameters. No differences were also seen regarding the histopathological analysis.

Conclusions We found no evidence that acupuncture at the LI4, SP6 and sacral points could be harmful to the Wistar rat dams.

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