A 47 year old man had suffered from chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) for eight years, and received conventional treatment from a university clinic without effect during the entire period. The patient presented for acupuncture treatment, complaining of constant pain in the perineal region, varying in severity from 5 to 9 on a 0 to 10 pain scale. After three treatments with acupuncture, the pain was reduced to 3.5; after a further three treatments the pain was reduced to 2.5; and after 10 months, the pain was reduced to either 2 or 3 and has remained stable for two years since then. The acupuncture points used were BL28, BL29 and KI3, all located within the S2–S4 segments. It seems likely that the reported beneficial effect may be due to the acupuncture treatment and further cases should be studied.